Profiles of Birch Sensitization (Bet v 1, Bet v 2, and Bet v 4) and Oral Allergy Syndrome Across Italy
نویسندگان
چکیده
منابع مشابه
Profiles of Birch Sensitization (Bet v 1, Bet v 2, and Bet v 4) and Oral Allergy Syndrome Across Italy.
BACKGROUND Birch allergy (BA) is a common pollinosis caused by the allergens Bet v 1, Bet v 2, and Bet v 4. Oral allergy syndrome (OAS) is frequently associated with BA. A gradient of sensitization to birch allergen across Europe has been reported. Therefore, this study aimed to investigate the birch sensitization profile, including OAS, across Italy. METHODS We performed a retrospective stud...
متن کاملDetection of specific IgE antibodies in sera of Japanese birch-allergic patients using recombinant allergens Bet v 1, Bet v 2 and Bet v 4.
BACKGROUND Birch pollen is the major allergen in pollinosis in northern Japan. IgE reactivity to individual birch pollen allergens has been shown to differ between populations of birch pollen-allergic patients living in different countries. In this study, we examined the IgE profiles to recombinant birch pollen allergens in birch-sensitive patients living in Sapporo. METHODS This study used t...
متن کاملHappy 25th birthday, Bet v 1!
As the deputy editor of WAOJ I am concentrating on basic science, but with continuous focus on the clinical relevance of submitted studies for our allergic and atopic patients. The questions that follow me are 1.) “What makes an allergen an allergen?” and 2.) “Why do humans and other mammalians form IgE?”. Within the period which I personally can oversee in the allergy field, i.e. roughly 25 ye...
متن کاملHuman TCR transgenic Bet v 1-specific Th1 cells suppress the effector function of Bet v 1-specific Th2 cells.
Pollinosis to birch pollen is a common type I allergy in the Northern Hemisphere. Moreover, birch pollen-allergic individuals sensitized to the major birch pollen allergen Bet v 1 frequently develop allergic reactions to stone fruits, hazelnuts, and certain vegetables due to immunological cross-reactivity. The major T cell epitope Bet v 1(142-153) plays an important role in cross-reactivity bet...
متن کاملChimeras of Bet v 1 and Api g 1 reveal heterogeneous IgE responses in patients with birch pollen allergy
BACKGROUND Characterization of IgE-binding epitopes of allergens and determination of their patient-specific relevance is crucial for the diagnosis and treatment of allergy. OBJECTIVE We sought to assess the contribution of specific surface areas of the major birch pollen allergen Bet v 1.0101 to binding IgE of individual patients. METHODS Four distinct areas of Bet v 1 representing in tota...
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ژورنال
عنوان ژورنال: Journal of Investigational Allergology and Clinical Immunology
سال: 2016
ISSN: 1018-9068
DOI: 10.18176/jiaci.0041